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| Use of heavy Trypan blue in macular hole surgery Eye advance online publication 12 February 2010; doi: 10.1038/eye.2010.3 Purpose: Intraocular dyes facilitate the identification of the inner limiting membrane (ILM) during surgery. Appropriate dyes should be safe, provide adequate staining, and be easy to use. Heavy Trypan blue eliminates the need for an air–fluid exchange (AFX) and appears to have little retinal toxicity. This study refers to a prospective, consecutive trial with heavy Trypan blue in macular hole surgery.
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