Key Points
- Epi-LASIK, performed with the Moria Epi-K, accounts for around one in four of Dr Josef Reiter's refractive surgery procedures.
In this article he describes his reasons for increasing his number of Epi-LASIK procedures and discusses some of the promising
results he has witnessed with the procedure so far. His studies, which have looked at the benefits of discarding or retaining
the epithelial sheet have still left him questioning the importance of its retention. However, he believes that, with the
correct therapeutic regimen, Epi-LASIK offers an excellent alternative to LASIK in safety-conscious patients and in some patients
who are not eligible for LASIK surgery.
 Figure 1
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I was interested in Epi-LASIK for several years before I began performing it myself. Drs Barry Soloway and Jorge Alió had
both reported very good early results. Then, in 2005, I saw some impressive results reported by a Slovenian surgeon — Dr Franc
Salamun of Nova Gorica — who had no complications and no stromal incursions after more than six months and 150 eyes treated.
In December of that year, I bought the Moria Epi-K and began performing Epi-LASIK.
One of my first Epi-LASIK patients was a 47-year old moderately myopic female. At day one and day three postoperatively, her
eyes looked beautifully clear, much better than the typical eye following PRK (Figures 1 & 2). By day three, re-epithelialization was complete, and the patient was not experiencing any pain at all. At the one-week
visit, I saw some cystoid epithelial changes, which then fully resolved. Overall, this patient had an excellent refractive
outcome at one month and one year, with no haze.
 Figure 2
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Epi-LASIK has subsequently become an important part of my surgical armamentarium, providing an option for safety-conscious
patients and those who would otherwise not qualify for refractive surgery. Epi-LASIK now accounts for about 20-25% of my refractive
practice.
My technique  Figure 3
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Our pre-, intra-, and postoperative medication regimen is listed in the sidebar. Of note is the importance of cyclopentolate in our pain control regimen — a key element in any surface ablation procedure.
I find that just one drop of cyclopentolate at the end of the surgery really increases patient comfort. We have also recently
added ibuprofen for one day preoperatively based on other surgeons' favourable experience with it. I would also like to stress
the importance of artificial tears, administered every 15 minutes, as well as Sumatriptan (Imigran, Imitrex) administered
immediately postoperatively and eight hours later in all patients. Patients rarely require Gabapentin.
I perform the epithelial separation in three steps:
- Step 1: I acquire good suction and begin the separation at Speed 1.
- Step 2: When the edge of the metal separator reaches the letter "K" in the word "Epi-K" engraved on the ring, I switch
to Speed 2.
- Step 3: After reaching the letter "i" in "Epi-K", I use the fast speed, Speed 3. As I do not keep the flap, I lift the
epikeratome away from the eye at the end of the forward pass. I use BSS continuously throughout the separation process
to keep the cornea lubricated. However, it is very important to dry the bed prior to the laser ablation.
I perform iris registration and a wavefront-guided ablation with the AMO Visx S4 IR laser system. If the ablation is deeper
than 75 µm I apply mitomycin C (MMC) 0.02% for 15 seconds. At the end of the case, I apply ice-cold BSS. This step is extremely
important for both comfort and healing.
In unusual cases where I reposition the flap, I like to flush it back into place with BSS, so that manipulation is minimized.
I wait 30-40 seconds then put a bandage contact lens on the eye.