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Saturday, 20 December 2014
Ophthalmology Times US - News
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mRNFL thickness helps identify glaucoma
December 19, 2014
Macular retinal nerve fibre layer (mRNFL) thickness measurements acquired using new spectral domain optical coherence tomography software can help ophthalmologists distinguish between eyes with glaucoma and those without the disease, states results of a recent study.
Small-gauge vitrectomy effective for PDR
December 18, 2014
Both 23-gauge and 25-gauge transconjunctival sutureless vitrectomy are equally effective for the treatment of proliferative diabetic retinopathy (PDR), according to a recently published study.
Stem cells could reduce need for corneal transplants
December 17, 2014
A treatment for corneal scars using stem cells grown from a tiny biopsy of a patient's undamaged eye one day could decrease the need for corneal transplants, according to mouse model experiments conducted by researchers at the University of Pittsburgh School of Medicine.
Combination therapy for wet AMD well-tolerated
December 12, 2014
Patients with subfoveal neovascular AMD whose disease was treated with a combination therapy, tolerated the therapy well and it resulted in the need for fewer re-treatments with ranibizumab, according to the findings of a Phase I study.
Topical cyclopentolate increases anterior chamber parameters
December 11, 2014
Researchers in Turkey have found that topical application of cyclopentolate hydrochloride 1% caused a statistically significant increase in ACD, ACA, ACV and pupil size in healthy children.
October 2014
Cover feature
Neuro-rescuing glaucomatous damage
By: Dr Tassos Georgiou MBChB, MRCOphth
In this article, the authors describe the use of high dose omega-3 fatty acids to combat the neuro-inflammation in glaucoma patients, thereby improving visual acuity and visual field in glaucoma patients.
New effective treatment for glaucoma patients sensitive to preservatives
Ophthalmic solutions in multiuse bottles must contain a preservative to maintain sterility. These preservatives, however, may have deleterious effects in patients with sensitivity to them. Therefore, preservative-free (PF) solutions for single-use are attractive. In this article, Dr Goldberg highlights the outcomes of his recent study assessing the efficacy of a PF formulation to lower IOP when compared with a preserved one.
Combining glaucoma therapies
By: Professor Norbert Pfeiffer
There are many factors to consider when trying to medically manage glaucoma. In this article, Prof Pfeiffer highlights best practices in choosing glaucoma medications as well as presenting why he believes fixed-dose combinations are advantageous.
Cataract and Refractive
Evaluating a new optical biometry device
By: Dr Jinhai Huang, Professor Qinmei Wang
Results of a study evaluating the AL-Scan in measurements of ocular components show that the repeatability and reproducibility were excellent for all parameters, except for WTW and PD; excluding WTW, good agreements were found between AL-Scan and IOLMaster; the 2.4-mm diameter K value may be the most reliable choice for calculation of IOL power with AL-Scan.
New double C-loop haptics improve stability for novel trifocal IOL technology
By: Cheryl Guttman Krader
A new trifocal IOL with double C-loop haptics (Micro F FineVision, PhysIOL) delivers excellent outcomes based on the benefits of its optic features and haptics.
Phakic IOLs: The ongoing evolution in refractive surgery
By: Cheryl Guttman Krader
Contemporary phakic IOLs are safe and effective for treating high ametropias. Further developments are expected to address some remaining needs, but the problem of complications due to interference with surrounding ocular tissues may never be overcome.
Retina
Shedding light on uveitis
By: Alastair Denniston
Recently, investigators from the UK and US demonstrated that standard SD-OCT can be used to generate optical density/signal intensity within the vitreous. Here, the authors highlight findings of their study.
Sirolimus for local delivery in the eye
By: Sri Mudumba, PhD, Dr Joel Naor, MSc, MBA
The authors describe a proprietary formuation of sirolimus for local injection that is currently in late-stage development for the treatment of noninfectious posterior-segment uveitis.
Glaucoma
Novel microshunt providing 'dramatic' lowering of IOP in small POAG series
By: Cheryl Guttman Krader, Dr Richard K. Parrish II
An investigational glaucoma device that shunts aqueous from the anterior chamber to a subconjunctival/ sub-Tenon's pouch is being evaluated in a prospective study of 35 eyes operated on at two centres.
How visual field loss impacts driving
By: Cheryl Guttman Krader, Dr Fiona C. Glen, PhD
Results of a randomized study show both superior and inferior visual field defects impair drivers' performance on the computerized Hazard Perception Test. However, superior visual field loss is associated with significantly greater worsening than inferior visual field loss.
Cornea
Corneal confocal microscopy after CXL for keratoconus
By: Nancy Groves, Dr David Touboul
Corneal confocal microscopy may be a useful tool for physicians performing corneal collagen crosslinking.
September 2014
Cover feature
Evaluating the safety profile of femtosecond LCS
In this article, Dr Conrad-Hengerer discusses a recent study investigating the impact of femtosecond laser-assisted surgery on anterior chamber flare values and macular thickness compared with standard phaco.
Laser refractive cataract surgery: Benefits in the eye of the beholder
By: Cheryl Guttman Krader
Controversy continues over whether the femtosecond laser provides advantages in cataract surgery that justify its added cost.
Mechanical devices to the rescue
By: Professor H. Burkhard Dick, MD, PhD
Prof. Dick discusses the challenges posed by a small pupil in femtosecond laser cataract surgery and the options that are available to surgeons to overcome pupil constriction.
Cataract and Refractive
Vision at all distances
The standard of care is implantation with an IOL, and with the introduction of a new lens to the European market, Dr Hamid and colleagues conducted a small trial to analyse the differences between this new option and other available lenses. Here, he presents his findings.
Comparison of emmetropic and low hyperope patients
Here, the author discusses the findings of a recent study examining the efficacy and safety of the Raindrop Near Vision Inlay in emmetropic presbyopes and then compares these with results from an unpublished study on patients with low hyperopia.
Long-term data for corneal inlay expanding outcomes for presbyopia
By: Lynda Charters
A small-aperture corneal inlay (Kamra, AcuFocus, Irvine, California, USA) for presbyopia yielded superb results in an analysis of long-term data.
Special Editorial
The Big 10
By: Felicity Thomas
We at OTEurope, wanted to look back over the last 10 years at what has changed over the years. In such a fast-paced industry, there have been monumental strides forward since the launch of this publication.
Retina
Managing CRVO and its complications
In a recent satellite symposium, sponsored by Bayer, the topic of macular oedema following CRVO was discussed by a panel of experts. Here, we present a summary of this meeting, highlighting the key outcomes.
Glaucoma
To penetrate or not to penetrate in glaucoma surgery?
In this article, comparative data is presented proving that trabeculectomy is more effective than non-penetrating options, however, does pose an increased risk of complications, leading to the conclusion that at the moment, procedures should be chosen on an individual basis.
Cornea
Corneal crosslinking shows favourable long-term outcomes
By: Cheryl Guttman Krader
Studies with follow-up of 2 to 6 years show that corneal crosslinking for progressive keratectasia is safe and induces long-term structural changes.
General
Cranial neuropathies in diabetes
There have been few studies primarily concerned with the relative frequencies and clinical characteristics of cranial neuropathies in diabetic subjects. Here, Dr Stefanucci gives a synopsis of the clinical characteristics and risk factors.
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Ophthalmology Times Europe is the independent source for current developments and best practices in European Ophthalmology. It is the balanced and unbiased forum for ophthalmologists to communicate practical experience, clinical knowledge, discoveries and applications, thereby promoting improvements in medical medical practice and patient health.
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